منابع مشابه
Cancer chemoprevention is not a failure.
Dear Sir: We read with much interest the review by J.Potter on ‘The failure of cancer chemoprevention’ (1). We, as well as most researchers working in the area of cancer chemoprevention, are as frustrated as Dr J.Potter is, about the lack of unequivocal evidence of a high benefit/ harm effect of cancer chemoprevention in clinical trials. However, we strongly feel that the failure of cancer chem...
متن کاملCancer Chemoprevention
1Biology Department, College of Science, UAE University, Al-Ain 17551, UAE 2Zoology Department, Faculty of Science, Cairo University, Cairo 12613, Egypt 3Department for Genetic Toxicology and Cancer Biology, National Institute of Biology, Večna Pot 111, Ljubljana, Slovenia 4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA 5Experimental Tum...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولChemoprevention of bladder cancer.
There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and the trace metal selenium. Other agents now being studied in the laboratory in...
متن کاملChemoprevention of Prostate Cancer
Prostate cancer (PCa) is a very heterogeneous disease with a wide spectrum of clinical presentations and consequences. Indeed, if microscopic foci of adenocarcinoma can be found in the prostate of many men, only a minority will progress to clinically relevant, symptomatic, or potentially lethal disease. This explains the striking difference between the incidence of PCa and its mortality rate. I...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2014
ISSN: 0143-3334,1460-2180
DOI: 10.1093/carcin/bgu063